Cork is anti-microbial, so there is no need to worry about germs, mold or mildew forming and no need to clean regularly, the cork sanitizes itself naturally. After practice, lay the mat flat to air dry. If there is dirt or body oils, wipe the mat down with a wet soft cloth with warm water. Every once in a while you can use mild soap with water before stains settle. And please DO NOT put your Scoria yoga mat in the washing machine.